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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDCD2L
All Species:
15.45
Human Site:
T249
Identified Species:
28.33
UniProt:
Q9BRP1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BRP1
NP_115722.1
358
39417
T249
I
I
K
S
G
D
Q
T
F
Y
K
F
M
K
R
Chimpanzee
Pan troglodytes
XP_001155058
358
39587
T249
I
I
K
S
G
D
Q
T
F
Y
K
F
M
K
R
Rhesus Macaque
Macaca mulatta
XP_001091018
371
40852
T257
V
I
K
S
G
D
Q
T
F
Y
K
F
M
K
R
Dog
Lupus familis
XP_541708
367
40221
T258
I
I
K
S
G
D
K
T
F
Y
K
F
M
K
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5N5
364
39937
F256
V
S
S
G
D
P
T
F
Y
R
F
M
K
R
I
Rat
Rattus norvegicus
P47816
287
32518
L193
K
F
K
S
K
I
A
L
E
P
E
Q
I
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510287
372
41694
F264
A
K
N
R
D
K
V
F
H
K
F
M
K
R
I
Chicken
Gallus gallus
Q5ZID2
379
41264
H269
T
K
V
R
S
G
D
H
T
F
H
K
F
M
K
Frog
Xenopus laevis
NP_001080804
361
40434
M255
K
H
E
T
K
D
D
M
V
F
N
N
F
K
K
Zebra Danio
Brachydanio rerio
NP_956517
357
39940
F246
A
K
H
G
D
D
T
F
T
G
F
M
K
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001119907
315
36990
K214
K
F
H
T
T
I
K
K
Y
P
D
Q
I
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781884
385
42522
T252
G
E
G
Y
E
K
V
T
A
K
H
G
D
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P25040
408
45975
T286
P
I
K
L
D
P
R
T
E
K
L
S
K
F
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.2
80.1
N.A.
70.8
26.2
N.A.
54.8
51.4
27.7
41.6
N.A.
N.A.
23.7
N.A.
27
Protein Similarity:
100
98.5
94.3
85.5
N.A.
80.4
41
N.A.
69.6
64.6
43.2
60.6
N.A.
N.A.
39.9
N.A.
43.1
P-Site Identity:
100
100
93.3
93.3
N.A.
0
20
N.A.
0
0
13.3
13.3
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
20
33.3
N.A.
6.6
13.3
40
13.3
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
8
0
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
31
47
16
0
0
0
8
0
8
0
0
% D
% Glu:
0
8
8
0
8
0
0
0
16
0
8
0
0
0
0
% E
% Phe:
0
16
0
0
0
0
0
24
31
16
24
31
16
8
0
% F
% Gly:
8
0
8
16
31
8
0
0
0
8
0
8
0
0
0
% G
% His:
0
8
16
0
0
0
0
8
8
0
16
0
0
0
0
% H
% Ile:
24
39
0
0
0
16
0
0
0
0
0
0
16
0
24
% I
% Lys:
24
24
47
0
16
16
16
8
0
24
31
8
31
47
16
% K
% Leu:
0
0
0
8
0
0
0
8
0
0
8
0
0
16
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
24
31
8
0
% M
% Asn:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% N
% Pro:
8
0
0
0
0
16
0
0
0
16
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
24
0
0
0
0
16
0
0
0
% Q
% Arg:
0
0
0
16
0
0
8
0
0
8
0
0
0
24
47
% R
% Ser:
0
8
8
39
8
0
0
0
0
0
0
8
0
0
0
% S
% Thr:
8
0
0
16
8
0
16
47
16
0
0
0
0
0
8
% T
% Val:
16
0
8
0
0
0
16
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
16
31
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _